Capability Statement

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Trusted Partner for Next-Generation Sequencing & Wastewater Genomics

North Wales Scientific delivers precision sequencing and wastewater-based pathogen detection services for federal, state, academic, and prime contractor partners. We offer a modular subcontracting model with CLIA-compliant workflows, advanced bioinformatics, and rapid turnaround. Our services support public health surveillance, research grants, and large-scale federal contracts.

Core Competencies

  • DNA/RNA extraction and isolation (clinical, environmental, wastewater)

  • High-throughput sequencing (Illumina, PacBio, Oxford Nanopore)

  • Amplicon, WGS, transcriptome, metagenomics workflows

  • Wastewater-based pathogen surveillance (CDC NWSS-aligned)

  • qPCR / RT-qPCR assays for SARS-CoV-2 and AMR targets

  • Custom assay development for federal grants and academic research

  • Bioinformatics reporting with secure cloud delivery

  • CLIA-compliant workflows available through certified lab partners

Technical Capabilities

    • Illumina NovaSeq / NextSeq / MiSeq

    • PacBio Sequel II / HiFi

    • Oxford Nanopore MinION / GridION

    • qPCR / RT-qPCR for SARS-CoV-2, AMR genes

    • Human clinical samples

      Environmental/wastewater concentrates

    • Microbial cultures, plasmids

    • Tissue, FFPE, low-input samples from nonclinical study animals

    • etc

    • Variant calling (GATK, DeepVariant)

    • RNA-seq quantification (STAR, Salmon)

    • Metagenomic assembly and binning

    • AMR gene detection and annotation

    • Secure, FISMA-ready cloud delivery

Wastewater Analysis & Surveillance

We provide end-to-end wastewater genomic analysis to support public health, environmental monitoring, and pathogen surveillance:

  • Sample concentration and nucleic acid extraction

  • qPCR / RT-qPCR assays for SARS-CoV-2, AMR targets

  • Amplicon sequencing for microbial community profiling (16S/18S/ITS)

  • Shotgun metagenomics for resistome and virome detection

  • CDC NWSS-aligned workflows and custom reporting dashboards

  • Ideal for municipal, state, and federal health departments

Key Differentiators

  • Modular subcontracting model for federal IDIQs and grants

  • Fast turnaround with surge testing capacity

  • Integration-ready with prime contractors’ LIMS and reporting systems

  • CLIA-compliant workflows via certified lab partners

  • Secure data pipelines supporting HIPAA, 21 CFR Part 11, and FISMA

  • Proven experience supporting large-scale surveillance initiatives

Prime Contractor Partnerships

We successfully partner with industry leaders to deliver specialized sequencing and analysis services:

✅ Quick Biology: High-throughput NGS, targeted panels, and custom assay development
✅ Sampled: CLIA-certified clinical sequencing and biobanking workflows
✅ New York Genome Center: Large-scale whole-genome and RNA-seq production with advanced informatics

These collaborations allow us to scale seamlessly, maintain rigorous quality standards, and meet complex federal contracting requirements.

NIH

DoD

CDC

NCI

USDA

NIH DoD CDC NCI USDA

Past Performance by Prime Contractors

  • NIH-funded infectious disease and pathogen surveillance initiatives

  • Academic subawards for cancer genomics and biomarker discovery

  • Environmental and public health sequencing for wastewater monitoring

  • Pharma and CRO partnerships for clinical trial assay support

SAM.gov Registered ✔️

CAGE Code: 9YT03

UEI: PC9UTJ8PSLT6

Small Business Classification: Small Business, Women Owned SB, Minority Owned SB

Primary NAICS Codes: 541714, 541380, 621511, 541690, 541519